The HIV/AIDS pandemic and its challenges have a longstanding impact on conditions that fall within the mission of the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). Responding to this challenge, NIAMS has published a Notice of Special Interest (NOSI) to promote research opportunities on HIV/AIDS (NOT-AR-23-004). Applications are being accepted through January 7, 2028.
The NOSI alerts potential applicants to the NIAMS of an area of special interest in HIV/AIDS-associated comorbidities that are within the Institute’s mission. NIH has provided the largest public investment in HIV/AIDS research globally. In line with overall NIH efforts, NIAMS encourages observational, translational, and basic/pre-clinical research focusing on how the presence or treatment of HIV/AIDS impacts systemic rheumatic, musculoskeletal and skin disease progression and pathogenesis, with a focus on utilization of existing HIV cohorts and repositories.
Projects should meet the NIH HIV/AIDS Research Priorities and Guidelines (NOT-OD-20-018). NIAMS is interested in supporting studies focused on, but not limited to:
- Investigating the impact of HIV infection, or anti-retroviral therapy (ART) on HIV/AIDS-associated comorbidities that are within the NIAMS mission.
- Studying the prevalence and risk assessment and management of HIV/AIDS-associated comorbidities in people living with HIV (PLWH).
- Identifying etiological targets or biomarkers along with mechanism of action for diagnosis or preclinical candidate therapeutic evaluation/development.
Examples of HIV/AIDS-associated comorbidities that are within the NIAMS mission are:
- Musculoskeletal pain.
- Muscle diseases (e.g., sarcopenia, cachexia, muscular dystrophy).
- Cartilage degeneration (e.g., osteoarthritis).
- Bone diseases (e.g., osteoporosis, osteopenia).
- Bone fracture.
- Arthritis and other rheumatic diseases (e.g., reactive arthritis, psoriatic arthritis, septic arthritis).
- Dermatological manifestations.
For more information on this initiative, please see:
Notice of Special Interest: Promoting Research Opportunities on HIV/AIDS in NIAMS
For inquiries, please contact:
Heiyoung Park, Ph.D.
Program Director, Scleroderma, Fibrosis, and Autoinflammatory Disease Program, NIAMS